Acne During Breast Cancer Treatment: Causes, Prevention, and Safe Management
Acne and skin rashes are surprisingly common side effects of breast cancer treatment. Many patients wonder: “Why do I suddenly have breakouts during chemotherapy or immunotherapy?”
This article explains the most common causes of acne during breast cancer treatment, how to tell the difference between acne and treatment-related rashes, and what you can do to care for your skin safely.
Why Does Acne Occur During Breast Cancer Treatment?
There are two primary reasons patients may notice acne-like changes:
1. Steroid-related acne
Corticosteroids like dexamethasone are often prescribed with chemotherapy to prevent nausea, vomiting, and drug reactions (such as with paclitaxel/Taxol or immunotherapy).
While essential for safety, steroids can cause acne, especially on the face, chest, and back.
2. Drug-reaction rashes
Some rashes from chemotherapy or immunotherapy may look like acne but are actually drug reactions.
Rashes from immunotherapy can be serious and may require medical intervention.
Patients should report any new or spreading rash immediately to their healthcare team.
Signs You Should Contact Your Doctor Right Away
A new or worsening rash that spreads quickly.
Red, painful, or itchy patches.
Skin changes while on immunotherapy.
Breakouts that don’t improve with gentle care.
Tip: Take a photo and upload it to your patient portal or share it with your care team. Don’t wait until your next scheduled visit.
Safe Skincare Tips During Cancer Treatment
Keep your skincare simple
Use fragrance-free lotions and cleansers.
Stick to products with just a few ingredients.
Avoid new laundry detergents or skincare products during treatment.
Be gentle with your skin
Don’t pick or pop acne.
Avoid harsh scrubs or exfoliants.
Pat your skin dry instead of rubbing.
Protect your skin from the sun
Cancer treatments make skin more sensitive.
Wear protective clothing and limit direct sun exposure.
Ask about treatment options
Doctors may prescribe oral or topical antibiotics.
Benzoyl peroxide gels or creams (OTC or prescription) may also help.
Always check that medications are not expired.
Key Takeaway
Acne during breast cancer treatment is common—and manageable.
It’s often caused by steroids or medication-related reactions. Gentle skincare, sun protection, and open communication with your medical team are essential.
If acne or rashes appear, don’t ignore them. With the right steps, you can keep your skin as healthy as possible during your cancer journey.
Reference
A long-time practicing oncologist and professor at the University of Michigan, Jennifer has received several awards for her medical excellence and published over 150 original research articles as well as numerous editorials and book chapters. She is also a speaker and advocate, committed to improving the quality of medical care and reducing the barriers to equity among the disenfranchised.
For more information on how HuMOLYTE can support your gut health during chemotherapy, visit our product page or consult your health care provider.
This blog was reviewed by Dr. Sourabh Kharait.
This blog is for educational purposes only and is not intended as medical advice. Always consult with your healthcare provider before making any changes to your treatment plan, hydration strategies, or diet. The information provided here is based on general insights and may not apply to individual circumstances.
